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Targeted Downregulation of Estradiol Binding Na+/H+ Exchanger Nhx-2, Mimics Calorie Restriction, Extends Reproductive Longevity and Ameliorates Effects Associated With Alpha Synuclein Aggregation In C. Elegans

2021-05-28

Abstract excerpt

<title>Abstract</title> <p>Setting in of reproductive senescence (RS) gives rise to several changes, making aged individuals susceptible to multiple disorders including neurodegenerative diseases, cardiovascular ailments and bone disorders amongst others. The present study, employing transgenic <italic>C. elegans</italic> that expresses ‘human’ alpha synuclein, endeavors to decipher the association of reproductiv...

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Literature Corpus work
9931f4be-cd70-51a9-a416-245c0a5b9bd2
DOI
10.21203/rs.3.rs-517539/v1
Open publication

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Targeted Downregulation of Estradiol Binding Na+/H+ Exchanger Nhx-2, Mimics Calorie Restriction, Extends Reproductive Longevity and Ameliorates Effects Associated With Alpha Synuclein Aggregation In C. ElegansDOI 10.21203/rs.3.rs-517539/v1
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