Article

New mechanistic insights from alignment of accessible chromatin and renal lineage factor DNA-binding with genetics of kidney function

2026-05-25

Abstract excerpt

<title>Abstract</title> <p> Genome-wide association studies for kidney function identified hundreds of genomic signals overlapping non-coding regions. Prioritizing regulated target genes is key to clarify mechanisms and discover novel therapeutic routes into kidney function preservation. Comprehensive alignment of variants credibly associated with estimated glomerular filtration rate with accessible chromatin ac...

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Literature Corpus work: dcbef903-e2a2-5ee8-85d4-6db04d3d456d
DOI: 10.21203/rs.3.rs-8000899/v1

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