Article

Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision

2021-04-17

Abstract excerpt

Severe falciparum malaria has substantially affected human evolution. Genetic association studies of patients with clinically defined severe malaria and matched population controls have helped characterise human genetic susceptibility to severe malaria, but phenotypic imprecision compromises discovered associations. In areas of high malaria transmission the diagnosis of severe malaria in young children and, in par...

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Literature Corpus work: dbf45656-9c96-5548-8da1-0cfe4a9632c5
DOI: 10.1101/2021.04.16.440107

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