Article

Genome-wide, time-sensitive interrogation of the heat shock response under diverse stressors via ReporterSeq

2020-03-30

Abstract excerpt

Interrogating cellular stress response pathways is challenging because of the complexity of regulatory mechanisms and response dynamics, which can vary with both time and the type of stress. We developed a reverse genetic method called ReporterSeq to comprehensively identify genes regulating a stress-induced transcription factor under multiple conditions in a time-resolved manner. ReporterSeq links RNA-encoded bar...

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Literature Corpus work: db7644d0-6f41-58b1-9790-5b856cf2a656
DOI: 10.1101/2020.03.29.014845

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