Article

Transcriptomics Unveil Canonical and Non-Canonical Heat Shock-Induced Pathways in Human Cell Lines

2024-12-23

Abstract excerpt

The cellular stress response (CSR) is a conserved mechanism that protects cells from environmental and physiological stressors. The heat shock response (HSR), a critical component of the CSR, utilizes molecular chaperones to mitigate proteotoxic stress caused by elevated temperatures. We hypothesized that while the canonical HSR pathways are conserved across cell types, specific cell lines may exhibit unique trans...

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Literature Corpus work: 3fabd195-6a35-55e3-bbf7-e228d3da88ed
DOI: 10.1101/2024.12.22.629972

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