Article

mDrop-seq: Massively parallel single-cell RNA-seq of <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>

2021-07-07

Abstract excerpt

Advances in high-throughput single-cell mRNA sequencing (scRNA-seq) have been limited till date by technical challenges like tough cell walls and low RNA quantity that prevented transcriptomic profiling of microbial species at throughput. We present microbial Drop-seq or mDrop-seq, a high-throughput scRNA-seq technique that is used on two yeast species, Saccharomyces cerevisiae , a popular model organism and Can...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b87ec44d-deec-52a0-ad14-a3ec4bc61f34
DOI: 10.1101/2021.07.06.451338

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

mDrop-seq: Massively parallel single-cell RNA-seq of <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>DOI 10.1101/2021.07.06.451338Read

mDrop-Seq: Massively Parallel Single-Cell RNA-Seq of Saccharomyces cerevisiae and Candida albicansSemantic proximity Read

<i>Candida albicans</i> exhibits heterogeneous and adaptive cytoprotective responses to anti-fungal compoundsSemantic proximity Read

Defining the transcriptomic landscape of <i>Candida glabrata</i> by RNA-SeqSemantic proximity Read

Candida albicans exhibits heterogeneous and adaptive cytoprotective responses to antifungal compoundsSemantic proximity Read

Roles of P-body factors in <i>Candida albicans</i> filamentation and stress responseSemantic proximity Read

Unstressed cells are alike, but stressed cells differ: Environmental and single-cell heterogeneity in yeast stress responsesSemantic proximity Read

Intra-species transcriptional profiling reveals key regulators of <i>Candida albicans</i> pathogenic traitsSemantic proximity Read

Genome-wide, time-sensitive interrogation of the heat shock response under diverse stressors via ReporterSeqSemantic proximity Read

Roles of P-body factors in Candida albicans filamentation and stress responseSemantic proximity Read

Droplet-based single cell RNA sequencing of bacteria identifies known and previously unseen cellular statesSemantic proximity Read

RNA Enrichment Method for Quantitative Transcriptional Analysis of Pathogens <i>In Vivo</i> Applied to the Fungus Candida albicansSemantic proximity Read

Identifying infection-associated genes of<i>Candida albicans</i>in the postgenomic eraSemantic proximity Read