Article

Unstressed cells are alike, but stressed cells differ: Environmental and single-cell heterogeneity in yeast stress responses

2025-03-14

Abstract excerpt

Cellular stress responses are central to survival, adaptation, and disease pathology, yet much of what we know comes from averages that mask heterogeneity. Using high-throughput single-cell RNA sequencing in Saccharomyces cerevisiae , we profiled approximately 13,000 cells exposed to diverse stresses. By annotating transposable elements (TEs) alongside coding genes, we captured expression across over 6,600 featur...

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Literature Corpus work: deb20dec-8656-599c-953f-3aa9a54b1eb2
DOI: 10.1101/2025.03.12.642837

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