Article

The structural basis for forkhead box family specificity revealed by the crystal structure of human FOXN1 in complex with DNA

2018-09-26

Abstract excerpt

<h4>Significance</h4> FOXN1 is a transcription factor that is essential for the development of the thymus and the production of T-lymphocytes. It is a member of a large family of transcription factors which recognize DNA sequences through the conserved Forkhead (FH) domain. FOXN1 recognizes a DNA sequence that is different from the common consensus binding sequence of FH domains, although key binding residues are...

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Literature Corpus work: db2b233a-c0bb-5b5d-94b1-fae631ab125e
DOI: 10.1101/428011

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