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Article

Essential structural and functional determinants within the forkhead domain of FOXC1.

Nucleic acids research - 1 Jan 2004

Saleem R A, Banerjee-Basu S, Murphy T C, Baxevanis A, Walter M A

Abstract excerpt

The forkhead domain (FHD)-containing developmental transcription factor FOXC1 is mutated in patients presenting with Axenfeld-Rieger malformations. In this paper, we report the introduction of positive, negative or neutral charged amino acids into critical positions within the forkhead domain of FOXC1 in an effort to better understand the essential structural and functional determinants within the FHD. We found...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15299087
DOI: 10.1093/nar/gkh742
PMCID: PMC514369

Genes

FOXC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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