Article
Crystal structure of a bZIP/DNA complex at 2.2 A: determinants of DNA specific recognition.
Journal of molecular biology - 8 Dec 1995
Keller W, König P, Richmond T J
Abstract excerpt
The X-ray structure of the GCN4-bZIP protein bound to DNA containing the ATF/CREB recognition sequence has been refined at 2.2 A. The water-mediated interactions between the basic domain and DNA are revealed, and combined with a more accurate description of the direct contacts, further clarify ho...
Topics
- Amino Acid Sequence
- Base Sequence
- Basic-Leucine Zipper Transcription Factors
- Binding Sites
- Crystallography, X-Ray
- Cyclic AMP Response Element-Binding Protein
- DNA
- DNA-Binding Proteins
- Fungal Proteins
- G-Box Binding Factors
- Macromolecular Substances
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Conformation
- Protein Kinases
- Saccharomyces cerevisiae Proteins