Article
Crystal structure of a bZIP/DNA complex at 2.2 A: determinants of DNA specific recognition.
Journal of molecular biology - 8 Dec 1995
Keller W, König P, Richmond T J
Abstract excerpt
The X-ray structure of the GCN4-bZIP protein bound to DNA containing the ATF/CREB recognition sequence has been refined at 2.2 A. The water-mediated interactions between the basic domain and DNA are revealed, and combined with a more accurate description of the direct contacts, further clarify how binding specificity is achieved. Water molecules extend the interactions of both invariant basic domain residues,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
