Article
Forkhead transcription factors: key players in health and disease.
Trends in genetics : TIG - 1 Jun 2011
Benayoun Bérénice A, Caburet Sandrine, Veitia Reiner A
Abstract excerpt
Forkhead box (FOX) proteins constitute an evolutionarily conserved family of transcription factors with a central role not only during development, but also in the adult organism. Thus, the misregulation and/or mutation of FOX genes often induce human genetic diseases, promote cancer or deregulate ageing. Indeed, germinal FOX gene mutations cause diseases ranging from infertility to language and/or speech...
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