Article

Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

2024-04-15

Abstract excerpt

Most genetic loci associated with complex traits and diseases through genome-wide association studies (GWAS) are noncoding, suggesting that the causal variants likely have gene regulatory effects. However, only a small number of loci have been linked to expression quantitative trait loci (eQTLs) detected currently. To better understand the potential reasons for many trait-associated loci lacking eQTL colocalizatio...

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Literature Corpus work: db0f9d44-93a6-5afa-95b9-8b8ce49c6651
DOI: 10.1101/2024.04.12.589213

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