Article

Impact of cell-type and context-dependent regulatory variants on human immune traits

2020-07-21

Abstract excerpt

The effects of trait-associated variants are often studied in a single relevant cell-type or context. However, for many complex traits, multiple cell-types are involved. This applies particularly to immune-related traits, for which many immune cell-types and contexts play a role. Here, we studied the impact of immune gene regulatory variants on complex traits to better understand genetic risk mediated through immu...

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Literature Corpus work: 6616c8c8-4874-5745-a3e8-15cf7537feab
DOI: 10.1101/2020.07.20.212753

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