Article

Increased expression of <i>Cd74</i> and MHC II genes by aortic macrophages links atherosclerosis with aging in mice

2026-07-21

Abstract excerpt

Atherosclerosis is a chronic inflammatory condition of the arteries leading to myocardial infarction, ischemic stroke and peripheral arterial diseases. Atherosclerotic plaques, which obstruct blood flow contain functionally diverse macrophage populations including pro-atherogenic and atheroprotective subsets. Aging is a major risk factor of atherosclerosis, but the mechanism underlying aging associated risk of ath...

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Literature Corpus work: daa9c2f6-cc34-535c-88ac-a44f4e4fb25a
DOI: 10.64898/2026.07.17.739099

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