Article

Integrated scRNA-seq analysis identifies conserved transcriptomic features of mononuclear phagocytes in mouse and human atherosclerosis

2020-12-10

Abstract excerpt

<h4>Rationale</h4> Accumulation of mononuclear phagocytes (monocytes, macrophages and dendritic cells) in the vessel wall is a hallmark of atherosclerosis. Although single-cell RNA-sequencing (scRNA-seq) has shed new light on immune cell transcriptional diversity in atherosclerosis, it is still unknown whether the transcriptional states of mononuclear phagocytes are conserved between mouse and human atheroscleros...

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Literature Corpus work: 73b3c16a-76c1-5709-aeec-1d951fb5fdce
DOI: 10.1101/2020.12.09.417535

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