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Article

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas.

Circulation research - 17 Jul 2020

Zernecke Alma, Winkels Holger, Cochain Clément, Williams Jesse W, Wolf Dennis, Soehnlein Oliver, Robbins Clint S, Monaco Claudia, Park Inhye, McNamara Coleen A, Binder Christoph J, Cybulsky Myron I, Scipione Corey A, Hedrick Catherine C, Galkina Elena V, Kyaw Tin, Ghosheh Yanal, Dinh Huy Q, Ley Klaus

Abstract excerpt

The diverse leukocyte infiltrate in atherosclerotic mouse aortas was recently analyzed in 9 single-cell RNA sequencing and 2 mass cytometry studies. In a comprehensive meta-analysis, we confirm 4 known macrophage subsets-resident, inflammatory, interferon-inducible cell, and Trem2 (triggering receptor expressed on myeloid cells-2) foamy macrophages-and identify a new macrophage subset resembling cavity...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32673538
DOI: 10.1161/CIRCRESAHA.120.316903
PMCID: PMC7371244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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