Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis.

Circulation research - 8 Jun 2018

Cochain Clément, Vafadarnejad Ehsan, Arampatzi Panagiota, Pelisek Jaroslav, Winkels Holger, Ley Klaus, Wolf Dennis, Saliba Antoine-Emmanuel, Zernecke Alma

Abstract excerpt

RATIONALE: It is assumed that atherosclerotic arteries contain several macrophage subsets endowed with specific functions. The precise identity of these subsets is poorly characterized as they have been defined by the expression of a restricted number of markers. OBJECTIVE: We have applied single-cell RNA sequencing as an unbiased profiling strategy to interrogate and classify aortic macrophage heterogeneity at...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aortic Diseases
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Leukocytes

Share to Monocytes

Share to Receptors, LDL

Share to Sequence Analysis, RNA

Share to Single-Cell Analysis

Source

Identifiers

PMID: 29545365
DOI: 10.1161/CIRCRESAHA.117.312509

Genes

TREM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis.PMID 29545365Read ↗

Integrated scRNA-seq analysis identifies conserved transcriptomic features of mononuclear phagocytes in mouse and human atherosclerosisSemantic proximity Read ↗

New Classification of Macrophages in Plaques: a Revolution.Semantic proximity Read ↗

Heterogeneity of macrophages in atherosclerosis revealed by single-cell RNA sequencing.Semantic proximity Read ↗

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas.Semantic proximity Read ↗

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry.Semantic proximity Read ↗

Macrophage heterogeneity in atherosclerosis: A matter of context.Semantic proximity Read ↗

Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed miceSemantic proximity Read ↗

Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaquesSemantic proximity Read ↗

High-Dimensional Single-Cell Multimodal Landscape of Human Carotid AtherosclerosisSemantic proximity Read ↗

A Review of Macrophage Diversity and Immune Checkpoint Regulation in Atherosclerosis: Insights from Single-Cell TranscriptomesSemantic proximity Read ↗

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.Semantic proximity Read ↗

Single-cell to pre-clinical evaluation of Trem2, Folr2, and Slc7a7 as macrophage-associated biomarkers for atherosclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.