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Article

Human assembloids

15 Oct 2022

Abstract excerpt

Deconstructing and then reconstructing developmental processes ex vivo is crucial to understanding how organs assemble and how physiology can be disrupted in disease. Human 3D stem cell-derived systems, such as organoids, have facilitated this pursuit; however, they often do not capture inter-tissue or inter-lineage cellular interactions that give rise to emergent tissue properties during development. Assembloids...

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PMID: 36317797
DOI: 10.1242/dev.201120

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