Article

Self-Organizing 3D Human Choroid Plexus-Ventricle-Cortical Organoids

2020-10-01

Abstract excerpt

<h4>ABSTRACT</h4> Both the choroid plexus (CP) and the cortex are derived from the rostral neural tube during early embryonic development. In addition to producing CSF, the CP secretes essential factors that orchestrate cortical development and later neurogenesis. Previous brain modeling efforts with human pluripotent stem cells (hPSCs) generated either cortical or CP tissues in 3D culture. Here, we used hPSC-der...

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Literature Corpus work: 9da358fa-b1f7-523d-abe8-1c5f3568ab5d
DOI: 10.1101/2020.09.30.321554

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