Back to search

Article

Neuromesodermal Progenitors Advance Network Formation of Spinal Neurons and Support Cells in Neural Ribbons <i>In Vitro</i> and Unprotected Survival in a Rat Subacute Contusion Model

2020-11-11

Abstract excerpt

Improved human stem cell interventions to treat CNS trauma requires continued expansion of in vitro models and delivery platforms to fill gaps in analysis and treatment. Transplanted neural stem cells (NSCs) face unique, multi-faceted challenges beyond survival that include differentiation, maturation, and integration into a complex cytokine-releasing microenvironment that impinges on a multipotent cell type. Alt...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
61a35571-fe61-5ad4-a03b-80293f01a870
DOI
10.1101/2020.11.10.374876
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Neuromesodermal Progenitors Advance Network Formation of Spinal Neurons and Support Cells in Neural Ribbons <i>In Vitro</i> and Unprotected Survival in a Rat Subacute Contusion ModelDOI 10.1101/2020.11.10.374876
Synchronous 3D patterning of diverse CNS progenitors generates motor neurons of broad axial identitySemantic proximity
Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications.Semantic proximity
Diversity of Adult Neural Stem and Progenitor Cells in Physiology and DiseaseSemantic proximity
Human microphysiological model of dorsal root ganglion-spinal cord dorsal horn circuitry recapitulates opioid induced effectsSemantic proximity
Oligodendrocytes in human iPS cell-derived cortical grafts remyelinate adult rat and human cortical neuronsSemantic proximity
Stem cells for spinal cord injury: Strategies to inform differentiation and transplantationSemantic proximity
Analysis of astrocyte progenitors derived from human induced pluripotent stem cells <i>in vitro</i> and following transplantation into the intact spinal cordSemantic proximity
Preparation of Neural Stem Cells and Progenitors: Neuronal Production and Grafting Applications.Semantic proximity
Human cortical neurons rapidly generated by direct ES cell programming integrate into stroke-injured rat cortexSemantic proximity
Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cellsSemantic proximity
A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells.Semantic proximity
Human spinal cord organoids recapitulate developmental and disease-associated oligodendrocyte lineage signaturesSemantic proximity
Select a neighboring publication to make it the new centre.