Article

A Transcriptionally Active DNA-Binding Site for Human p53 Protein Complexes

1992-06-01

Abstract excerpt

Recent studies have demonstrated transcriptional activation domains within the tumor suppressor protein p53, while others have described specific DNA-binding sites for p53, implying that the protein may act as a transcriptional regulatory factor. We have used a reiterative selection procedure (CASTing: cyclic amplification and selection of targets) to identify new specific binding sites for p53, using nuclear extr...

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Literature Corpus work: d9d3bd8e-520c-501c-ab14-fb0dbaec194f
DOI: 10.1128/mcb.12.6.2866-2871.1992

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