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Article

Characterisation of DNA binding and transcriptional regulatory function of an endogenous mutant p53 in MDA-468 human breast cancer cells.

Biochemical and biophysical research communications - 6 Mar 1997

Prasad K A, Church J G

Abstract excerpt

Tumour suppressor p53, the most frequently altered gene among human cancers, is known to function by modifying gene transcription. Transcriptional regulatory activity of p53 has been established using transfected cell culture models and in vitro systems. Here, we report the characterisation of transcriptional function of an endogenous mutant p53 (p53(273.His)) in MDA-468 human breast cancer cells, in terms of...

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Source

Identifiers

PMID: 9125118
DOI: 10.1006/bbrc.1997.6212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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