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Article

Cloning and characterization of murine p53 upstream sequences reveals additional positive transcriptional regulatory elements.

Gene - 22 Aug 2001

Reisman D, Eaton E, McMillin D, Doudican N A, Boggs K

Abstract excerpt

Transcriptional regulation of the p53 gene plays an important role leading to elevated expression of mutant p53 alleles in tumor cells. In addition, alterations in p53 transcription levels occur in response to changes in the cell cycle. Previous work had identified a number of regulatory sites at the 5'-end of the murine p53 promoter. During the characterization of the 5'-end of the cloned murine p53 promoter, we...

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Identifiers

PMID: 11675005
DOI: 10.1016/s0378-1119(01)00623-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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