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Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches

1 Nov 2001

Abstract excerpt

The completion of the human genome sequence (International Human Genome Sequence Consortium (2001) Nature 409, 860-921; Venter, J. C., et al. (2001) Science 291, 1304-1351) allows for new ways to analyze global cellular regulatory mechanisms. Here we present a strategy to identify genes regulated by specific transcription factors in the human genome, and apply it to p53. We first collected promoters or introns of...

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PMID: 11571296
DOI: 10.1074/jbc.m106570200

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