Article

A Fast Lasso-Based Method for Inferring Pairwise Interactions

2021-01-30

Abstract excerpt

<h4> A bstract </h4> Large-scale genotype-phenotype screens provide a wealth of data for identifying molecular alternations associated with a phenotype. Epistatic effects play an important role in such association studies. For example, siRNA perturbation screens can be used to identify pairwise gene-silencing effects. In bacteria, epistasis has practical consequences in determining antimicrobial resistance as t...

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Literature Corpus work: d9a67491-abcd-5aae-92d3-29a728c865f9
DOI: 10.1101/2021.01.28.428698

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