Article

A Fast Lasso-Based Method for Inferring Higher-Order Interactions

2021-12-14

Abstract excerpt

<h4> A bstract </h4> Large-scale genotype-phenotype screens provide a wealth of data for identifying molecular alterations associated with a phenotype. Epistatic effects play an important role in such association studies. For example, siRNA perturbation screens can be used to identify combinatorial gene-silencing effects. In bacteria, epistasis has practical consequences in determining antimicrobial resistance...

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Literature Corpus work: f55d4d74-1498-547f-8c13-37b3bbfa5be3
DOI: 10.1101/2021.12.13.471844

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