Article
Screen and clean: a tool for identifying interactions in genome-wide association studies.
Genetic epidemiology - 1 Apr 2010
Wu Jing, Devlin Bernie, Ringquist Steven, Trucco Massimo, Roeder Kathryn
Abstract excerpt
Epistasis could be an important source of risk for disease. How interacting loci might be discovered is an open question for genome-wide association studies (GWAS). Most researchers limit their statistical analyses to testing individual pairwise interactions (i.e., marginal tests for association). A more effective means of identifying important predictors is to fit models that include many predictors...
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