Article
Eigen-Epistasis for detecting gene-gene interactions.
BMC bioinformatics - 23 Jan 2017
Stanislas Virginie, Dalmasso Cyril, Ambroise Christophe
Abstract excerpt
BACKGROUND: A large amount of research has been devoted to the detection and investigation of epistatic interactions in genome-wide association studies (GWASs). Most of the literature focuses on low-order interactions between single-nucleotide polymorphisms (SNPs) with significant main effects. RESULTS: In this paper we propose an original approach for detecting epistasis at the gene level, without systematically...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.