Article

PAN-GWES: Pangenome-spanning epistasis and co-selection analysis via de Bruijn graphs

2023-09-08

Abstract excerpt

Studies of bacterial adaptation and evolution are hampered by the difficulty of measuring traits such as virulence, drug resistance and transmissibility in large populations. In contrast, it is now feasible to obtain high-quality complete assemblies of many bacterial genomes thanks to scalable and affordable long-read sequencing technology. To exploit this opportunity we introduce a phenotype- and alignment-free m...

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Literature Corpus work: 16206c6b-998c-58fa-b824-c48eedf42ab5
DOI: 10.1101/2023.09.07.556769

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