Article

Epigenomic profiling of active regulatory elements by enrichment of unmodified CpG dinucleotides

2024-02-16

Abstract excerpt

Current approaches for the study of DNA methylation and other modified bases focus on the modified fraction of the genome and are particularly well-suited to the detection of DNA hypermethylation. However, the study of hypomethylation (loss of DNA methylation), which is typically associated with markers of active chromatin, has been largely overlooked, in part, due to the lack of a suitable methodology. We present...

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Literature Corpus work: d9120240-3e18-53bb-b362-d0788125a096
DOI: 10.1101/2024.02.16.575381

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