Article

Simultaneous epigenomic profiling and regulatory activity measurement using e2MPRA

2025-06-30

Abstract excerpt

C is- regulatory elements (CREs) have a major effect on phenotypes including disease. They are identified in a genome-wide manner by analyzing the binding of transcription factors (TFs), various co-factors and histone modifications in DNA using assays such as ChIP-seq, Cut&Tag and ATAC-seq. However, these assays are descriptive and require high-throughput technologies, such as massively parallel reporter assays (...

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Literature Corpus work: d81aed76-12ef-5578-b913-379bea54589f
DOI: 10.1101/2025.06.26.661849

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