Article
Mediators and dynamics of DNA methylation.
Wiley interdisciplinary reviews. Systems biology and medicine - 1 Jan 2000
Shoemaker Robert, Wang Wei, Zhang Kun
Abstract excerpt
As an inherited epigenetic marker occurring mainly on cytosines at CpG dinucleotides, DNA methylation occurs across many higher eukaryotic organisms. Looking at methylation patterns genome-wide classifies cell types uniquely and in several cases discriminates between healthy and cancerous cell types. DNA methylation can occur allele-specifically, which allows the cellular regulatory machinery to recognize each...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
