Article

DNA methylation oscillation defines classes of enhancers

2018-02-08

Abstract excerpt

Understanding the regulatory landscape of human cells requires the integration of genomic and epigenomic maps, capturing combinatorial levels of cell type-specific and invariant activity states. Here, we segmented whole-genome bisulfite sequencing-derived methylomes into consecutive blocks of co-methylation (COMETs) to obtain spatial variation patterns of DNA methylation (DNAm oscillations) integrated with histone...

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Literature Corpus work: 63c6d00f-15f0-50c2-aceb-ce49d72c8a67
DOI: 10.1101/262212

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