Article
The Genetics and Functional Genomics of Osteoarthritis.
Annual review of genomics and human genetics - 1 Aug 2024
Arruda Ana Luiza, Katsoula Georgia, Chen Shibo, Reimann Ene, Kreitmaier Peter, Zeggini Eleftheria
Abstract excerpt
Osteoarthritis is the most prevalent whole-joint degenerative disorder, and is characterized by the degradation of articular cartilage and the underlying bone structures. Almost 600 million people are affected by osteoarthritis worldwide. No curative treatments are available, and management strategies focus mostly on pain relief. Here, we provide a comprehensive overview of the available human genetic and...
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