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Article

The epigenomic landscape of primary tissues in osteoarthritis.

Annals of the rheumatic diseases - 1 Aug 2026

Kreitmaier Peter, Stergiou Odysseas Sotirios, Katsoula Georgia, Tutino Mauro, Bittner Norbert, Shah Karan M, Swift Diane, Wilkinson Jeremy Mark, Zeggini Eleftheria

Abstract excerpt

OBJECTIVES: Osteoarthritis is a complex joint disease, affecting more than 500 million people worldwide. We investigated DNA methylation profiles and integrated these with matching genotype and transcriptomics data in primary tissues of patients with knee osteoarthritis to enhance our understanding of the regulatory framework that modulates gene expression in osteoarthritis. METHODS: We measured matched genotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41748390
DOI: 10.1016/j.ard.2026.01.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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