Article

Luks-PV induce HOXA9 degradation through autophagy in Acute myeloid leukemia with HOXA9 overexpression

2022-07-15

Abstract excerpt

<h4>Background: </h4> Our previous studies have demonstrated that Luks-PV have good anti-leukemia ability effects and could possibly be a promising therapy for adult acute myeloid leukemia (AML). Aberrant over-expression of HOXA9 is a prominent feature of AML driven by multiple oncogenes, and therapeutic degrading of HOXA9 may be an effective treatment strategy in AML. This paper focused on the Luks-PV-regulating...

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Literature Corpus work: d84a22e3-592f-53dd-a60e-e76aac4c96ba
DOI: 10.21203/rs.3.rs-56347/v2

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