Article

lncRNA HOXA-AS2 functions as an oncogene by binding to EZH2 and suppressing LATS2 in Acute myeloid leukemia (AML)

2020-09-08

Abstract excerpt

<h4>Background: </h4> Long noncoding RNAs (lncRNAs) plays an important role in the development of physiology and pathology. Many reports have shown that lncRNA HOXA cluster antisense RNA 2 (HOXA-AS2) is a carcinogen and plays an important role in many tumors, but little is known about its role in Acute myeloid leukemia (AML). MethodsThe expression of HOXA-AS2 in AML cell line was detected by qRT-PCR. AML cases fro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ebfc187d-2a51-501b-bd96-b847e13f47d9
DOI: 10.21203/rs.3.rs-70829/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

lncRNA HOXA-AS2 functions as an oncogene by binding to EZH2 and suppressing LATS2 in Acute myeloid leukemia (AML)DOI 10.21203/rs.3.rs-70829/v1Read

Long Noncoding RNA HOXA-AS2 Functions as an Oncogene by Binding to EZH2 and Suppressing LATS2 in AMLSemantic proximity Read

Overexpression of long noncoding RNA HOXA‐AS2 predicts an adverse prognosis and promotes tumorigenesis via SOX4/PI3K/AKT pathway in acute myeloid leukemiaSemantic proximity Read

Long non-coding RNA HOXA-AS2 may serve as a new therapeutic target and promising prognostic market for most of cancersSemantic proximity Read

The Role of the HOXA Gene Family in Acute Myeloid LeukemiaSemantic proximity Read

HOXA11 antisense long noncoding RNA (HOXA11-AS): A promising lncRNA in human cancers.Semantic proximity Read

High HSPA8 expression predicts adverse outcomes of acute myeloid leukemia.Semantic proximity Read

Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemiaSemantic proximity Read

Overexpression of HOXA10 is associated with unfavorable prognosis of acute myeloid leukemiaSemantic proximity Read

TCF7L2 activated HOXA-AS2 decreased the glucocorticoid sensitivity in acute lymphoblastic leukemia through regulating HOXA3/EGFR/Ras/Raf/MEK/ERK pathwaySemantic proximity Read

Long noncoding RNAs: pivotal regulators in acute myeloid leukemiaSemantic proximity Read

Overexpression of long non-coding RNA HOTAIR predicts a poor prognosis in patients with acute myeloid leukemiaSemantic proximity Read

Highly expressed HOXD-AS2 promotes the proliferation of cancer cell and leads to poor prognosis of colorectal cancer via TGF-β signaling pathway.Semantic proximity Read