Article

Luks-pv Induces Apoptosis Through Methyltransferase Set8 in Human Acute Myeloid Leukaemia Cells

2020-06-23

Abstract excerpt

<h4>Background: </h4> We previously reported that LukS-PV induces apoptosis in human acute myeloid leukaemia (AML) cells. Furthermore, SET8 is a member of the SET domain-containing methyltransferase family and overexpressed in numerous tumours, including AML and indicated a poor prognosis. However, it is unclear whether LukS-PV induce apoptosis via SET8. In current study, we aimed to investigate the regulatory mec...

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Literature Corpus work: b546b22a-5862-5800-aa71-ab381413022d
DOI: 10.21203/rs.3.rs-36930/v1

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