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The dual role of autophagy in acute myeloid leukemia

7 May 2022

Abstract excerpt

Acute myeloid leukemia (AML) is a severe hematologic malignancy prevalent in older patients, and the identification of potential therapeutic targets for AML is problematic. Autophagy is a lysosome-dependent catabolic pathway involved in the tumorigenesis and/or treatment of various cancers. Mounting evidence has suggested that autophagy plays a critical role in the initiation and progression of AML and anticancer...

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PMID: 35526025
DOI: 10.1186/s13045-022-01262-y

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