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METTL3 affects FLT3-ITD+ Acute Myeloid Leukemia by mediating autophagy by regulating PSMA3-AS1 stability

2022-06-24

Abstract excerpt

<h4>Objective: </h4> The study was designed to explore the role of PSMA3-AS1 in initiation and progression of acute myeloid leukemia (AML) and investigate its action mechanism. Methods Expression of PSMA3-AS1, miR-20a-5p and ATG16L1 both in vitro and in vivo was measured by qRT-PCR. The expression of protein was detected by western blot assay. Edu staining and flow cytometry were utilized to measure cell prolifer...

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Literature Corpus work
21f9a3f7-bc31-5615-afc9-5372e5fdbe68
DOI
10.21203/rs.3.rs-1700325/v2
Open publication

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METTL3 affects FLT3-ITD+ Acute Myeloid Leukemia by mediating autophagy by regulating PSMA3-AS1 stabilityDOI 10.21203/rs.3.rs-1700325/v2
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