Article

Shisa7 phosphorylation regulates GABAergic transmission and neurodevelopmental behaviors

2021-08-04

Abstract excerpt

GABA-A receptors (GABA A Rs) are crucial for development and regulation of the central nervous system. Altered GABAergic signaling is hypothesized to be involved in the pathophysiology of neurodevelopmental disorders. Nevertheless, how aberrant cellular and molecular mechanisms affect GABA A Rs in these diseases remain elusive. Recently, we identified Shisa7 as a GABA A R auxiliary subunit that modulates GABA...

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Literature Corpus work: d831e04b-c992-5644-81c6-e64ae9436ecc
DOI: 10.1101/2021.08.02.454792

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