Article
Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice.
Neuropharmacology - 1 Jan 2017
Lim Chae-Seok, Kim Hyopil, Yu Nam-Kyung, Kang Sukjae Joshua, Kim TaeHyun, Ko Hyoung-Gon, Lee Jaehyun, Yang Jung-Eun, Ryu Hyun-Hee, Park Taesung, Gim Jungsoo, Nam Hye Jin, Baek Sung Hee, Wegener Stephanie, Schmitz Dietmar, Boeckers Tobias M, Lee Min Goo, Kim Eunjoon, Lee Jae-Hyung, Lee Yong-Seok, Kaang Bong-Kiun
Abstract excerpt
Autism spectrum disorders (ASDs) are a group of developmental disorders that cause variable and heterogeneous phenotypes across three behavioral domains such as atypical social behavior, disrupted communications, and highly restricted and repetitive behaviors. In addition to these core symptoms, other neurological abnormalities are associated with ASD, including intellectual disability (ID). However, the...
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