Article

DEGRONOPEDIA - a web server for proteome-wide inspection of degrons

2022-05-22

Abstract excerpt

<h4>ABSTRACT</h4> The ubiquitin-proteasome system is a proteolytic pathway that removes damaged and unwanted proteins. Their selective turnover is initiated by ubiquitin (Ub) attachment, mainly by Ub ligases that recognize substrates through their short linear motifs termed degrons. A degradation-targeting degron comprises a nearby Ub-modified residue and an intrinsically disordered region (IDR) involved in inter...

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Literature Corpus work: d80535c7-4432-564c-bdfc-3c628e8ceae8
DOI: 10.1101/2022.05.19.492622

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