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Survey of the human proteostasis network: the ubiquitin-proteasome system

2026-03-16

Abstract excerpt

<h4>SUMMARY</h4> Modification by ubiquitination governs the half-lives of thousands of proteins that are fated for elimination by either the proteasome or autophagy pathways, depending on the intricate architectures of ubiquitin modification. This system mediates quality control for individual proteins, protein complexes, and organelles, as well as myriad purely regulatory functions. Here we provide a comprehensi...

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Literature Corpus work
42edce3b-61ee-5bac-9980-76dd045ccb08
DOI
10.64898/2026.03.13.711689
Open publication

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Survey of the human proteostasis network: the ubiquitin-proteasome systemDOI 10.64898/2026.03.13.711689
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