Article

High-throughput TCRB enrichment sequencing of human cord blood exhibited a distinct fetal T cell repertoire in the third trimester of pregnancy

2022-09-12

Abstract excerpt

<h4>Study question</h4> What are the molecular characteristics during the maturation process of the human fetal immune system in the third trimester of pregnancy? <h4>Summary answer</h4> Both the diversity and length of complementarity determining region 3 (CDR3s) in the fetal TCRB repertoire were less than those of adult CDR3s, and the fetal CDR3 length increased with gestation weeks in late pregnancy. <h4>What...

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Literature Corpus work: d7d766aa-65c6-5019-b8a8-acafcd3f23e8
DOI: 10.1101/2022.09.08.506871

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