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Article

T Cell Repertoire During Ontogeny and Characteristics in Inflammatory Disorders in Adults and Childhood.

Frontiers in immunology - 1 Jan 2020

Foth Svenja, Völkel Sara, Bauersachs Daniel, Zemlin Michael, Skevaki Chrysanthi

Abstract excerpt

Since the first day of life, a newborn has to deal with various pathogens from the environment. While passive immune protection is provided by diaplacental maternal antibodies, the development of cellular immunity is ongoing. A mature immune system should be able not only to defend against pathogens, but should also be able to differentiate between self- and non-self-antigens. Dysregulation in the development of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33633732
DOI: 10.3389/fimmu.2020.611573
PMCID: PMC7899981

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