Article
Analysis of the Repertoire Features of TCR Beta Chain CDR3 in Human by High-Throughput Sequencing.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016
Hou Xianliang, Wang Mingbang, Lu Chong, Xie Qian, Cui Guangying, Chen Jianing, Du Yu, Dai Yong, Diao Hongyan
Abstract excerpt
BACKGROUND/AIMS: To ward off a wide variety of pathogens, the human adaptive immune system harbors a vast array of T-cell receptors, collectively referred to as the TCR repertoire. Assessment of the repertoire features of TCR is vital for us to deeper understand of immune behaviour and immune response. METHODS: In this study, we used a combination of multiplex-PCR, Illumina sequencing and IMGT...
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