Article
Survival of the fetus: fetal B and T cell receptor repertoire development.
Seminars in immunopathology - 1 Nov 2017
Rechavi Erez, Somech Raz
Abstract excerpt
A mature and diverse T and B cell receptor repertoire is a prerequisite for immunocompetence. In light of its increased susceptibility to infection, the human fetus has long been considered deficient in this regard. However, data accumulated since the 1990s and in earnest in the past couple of years paints a more complicated picture. As we describe in this review, mechanisms responsible for generating a diverse...
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