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Article

TRIM9 switches the morphological phenotype of melanoma cells

2026-03-18

Abstract excerpt

Melanoma is a highly plastic cancer characterized by distinct cellular phenotypes associated with broadly unique gene expression profiles. TRIM9 is a brain-enriched E3 ubiquitin ligase detected in melanoma, but how TRIM9 expression regulates melanoma phenotype is unknown. Using two metastatic human melanoma cell lines and a mouse melanoma model, we found that TRIM9 promoted melanoma proliferation and altered cell...

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Identifiers and source

Literature Corpus work
d721826b-ba9a-51b5-ba9e-161d82f57a07
DOI
10.64898/2026.03.17.712420
Open publication

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TRIM9 switches the morphological phenotype of melanoma cellsDOI 10.64898/2026.03.17.712420
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