Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis

17 Aug 2019

Abstract excerpt

OBJECTIVE: To understand role of barrier molecules in melanomas. BACKGROUND: We have reported poor patient survival and low immune infiltration of melanomas that overexpress a set of genes that include filaggrin (FLG), dystonin (DST), junction plakoglobin (JUP), and plakophilin-3 (PKP3), and are involved in cell-cell adhesions. We hypothesized that these associations are causal, either by interfering with immune...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Mast cells and histamine
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31425296
DOI: 10.1097/sla.0000000000003522

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and AngiogenesisPMID 31425296Read ↗

Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor.Semantic proximity Read ↗

Molecular events in melanoma development and progressionSemantic proximity Read ↗

Cell Adhesion Molecules in Normal Skin and MelanomaSemantic proximity Read ↗

TRIM9 switches the morphological phenotype of melanoma cellsSemantic proximity Read ↗

Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAF <sup>V600E</sup> -induced cellular senescence in human melanocytesSemantic proximity Read ↗

PSGL-1 blockade delays relapse to BRAF/MEK inhibition in cutaneous melanomaSemantic proximity Read ↗

A Gene Expression Signature of Invasive Potential in Metastatic Melanoma CellsSemantic proximity Read ↗

Desmosome mutations impact the tumor microenvironment to promote melanoma proliferationSemantic proximity Read ↗

Loss of NECTIN1 triggers melanoma dissemination upon local IGF1 depletionSemantic proximity Read ↗

Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanomaSemantic proximity Read ↗

CCN4 shifts melanoma cells from a fragile proliferative state to a resilient metastatic stateSemantic proximity Read ↗

The role of N-Cadherin, MCAM, and β3 integrin in melanoma progression, proliferation, migration and invasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.